Does a normal B550M motherboard support nvidia tesla k80?

Or a commercial gpu needs commercial motherboard?

By commercial you are meaning enterprise right? . In that case an enterprise hardware like a enterprise gpu will work in consumer motherboards. But it may not be able to use advanced features offered by the enterprise GPU. Like GPU virtualization.

Yes I meant enterprise. But tesla k80 doesn’t seem to have a fan, can the heat be managed on consumer grade motherboard?

yes the heat can be managed my manually adding the cooling fan to Tesla k80 by removing top cover of GPU, it is equipped with 3 heat sinks , you can mount two or three fans accordingly.

Tesla K80 is designed for servers in data center where they have environment control so external cooling fans are not required.

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